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extrapyramidal system |
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extrapyramidal system [¦ek·strə‚pir·ə′mid·əl ′sis·təm] (neuroscience) Descending tracts of nerve fibers arising in the cortex and subcortical motor areas of the brain. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In squirrel monkeys, l-sulpiride has been found to exert strong anti-motion sickness effects and no extrapyramidal side effects at the dosing levels studied. Among the most serious are extrapyramidal side effects (EPS), which include dystonic reactions, akathisia, and parkinsonism. BL-1020 is an orally available GABA enhanced antipsychotic for the treatment of schizophrenia that was shown in preclinical studies to retain the efficacy of currently available typical and atypical antipsychotic drugs while achieving a much higher safety profile as evidenced by a lack of metabolic or extrapyramidal side effects. |
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