forced expiratory volume

(redirected from FEV1)
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forced expiratory volume

[¦fȯrst ik¦spī·rə‚tȯr·ē ′väl·yəm]
(medicine)
During the performance of a forced vital capacity measurement, the volume of exhaled gas over a specific time interval.
References in periodicals archive ?
In the high eosinophils patient group: Mean improvements from baseline in FEV1 (and mean percent change in FEV1) at 12 weeks, the primary (and a secondary) endpoint of the study were: 390ml (26 percent) dupilumab 300 mg every other week (Q2W); 430 ml (26 percent) dupilumab 200 mg Q2W; 180 ml (10 percent) placebo.
In the Tuscan Epidemiologic Study of Airways Obstructive Disease done by Camilli et al, 18 they noted that even among those with severe COPD (defined as FEV1 less than 50% of predicted), less than a quarter died due to COPD but in nearly 50% the primary cause of death was due to cardiovascular causes.
The first co-primary endpoint consisted of the comparison between the fixed dose combinations of aclidinium/formoterol 400/12mcg and 400/6mcg versus aclidinium alone in change from baseline in FEV1 at 1 hour post-dose at week 24.
The average healthy person should be able to expire 80% or more of her predicted FEV1 in the first second of maximum expiration.
The diagnosis of acute exacerbation of cystic fibrosis was made, when at least two of the following conditions were present: fever, newly-onset or increased cough or sputum production, hemoptysis, dyspnea, chest pain, fatigue, loss of appetite, a decrease of more than 10% in FEV1 or FVC and deterioration of pulmonary sounds (26).
The measurement of FEV1 before and after our type of breathing exercises makes it abundantly clear that in the vast majority of asthmatics in this age group, bronchial obstruction is not increased, but in fact the airways are less obstructed.
In our study COPD patients without macrocytosis had significantly lower FEV1 levels and slightly, but not significantly, higher dyspnea scores.
An increase in 12% in FEV1 indicated a positive response to bronchodilator.
All were followed up every month for clinical assessment and FEV1 for at least 12 months.
Lung volume reduction surgery improves the BODE index in patients with severe COPD as a result of changes in FEV1 and dyspnoea score (Lederer et al 2007).