immunoassay

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Related to FPIA: fluorescence polarization immunoassay, EFPIA

Immunoassay

An assay that quantifies antigen or antibody by immunochemical means. The antigen can be a relatively simple substance such as a drug, or a complex one such as a protein or a virus. See Antibody, Antigen

The reactants are first mixed so that a varying quantity of one (A) is added to a constant amount of the other (B). The formation of an immune (antigen-antibody) complex is measured as a function of the varied reactant (A). The result is represented by a “standard curve” for reactant A. An unknown sample is tested by adding it to reactant B. The extent of the measured change is referred to the standard curve, and thereby is obtained the amount of reactant A which produces a comparable change. The amount is represented as the content of reactant A in the unknown sample. See Immunofluorescence, Immunology, Radioimmunoassay

immunoassay

[‚im·yə·nō′a‚sāy]
(immunology)
A laboratory detection method that uses antibodies to react with specific substances.
References in periodicals archive ?
As we looked at our work on the FPIA project over the last 18 months, we could not see the project generating positive economic value added (EVA) for our shareholders for quite some time.
2] administration, MTX concentrations measured by FPIA were comparable to those obtained by LC-MS/MS (Fig.
Negative results for all urine samples were obtained with the Abbott FPIA, whereas the Mahsan-AM[P.
7] Nonstandard abbreviations: tHcy, total homocysteine; CVD, cardiovascular disease; MMA, methylmalonic acid; FPIA, fluorescence polarization immunoassay; GC-MS, gas chromatography-mass spectrometry; MS-MS, tandem mass spectrometry; MTHFR, methylenetetrahydrofolate reductase; CBS, cystathionine 0-synthase; NTD, neural tube defect; and holoTC, holotranscobalamin.
Carter, president and CEO, said, "As a result of slower sales growth, declining gross margins and the need to make substantial investments in our FPIA development program, we have made a decision to downsize our work force by approximately 40 positions, or 10 percent.
In surveys 2 and 3, tHcy was measured by the FPIA method 7 of 23 and 6 of 17 times, respectively.
Response of AxSYM FPIA assay for amphetamines after addition of heptaminol to drug-free urine.
We can also exclude that the higher MEGX concentrations observed in uremic patients were the result of positive interferences with the TDx FPIA by substances that had accumulated in uremic plasma because the predose (0 min) value was subtracted from values obtained at the various postinjection times.
KCT, antibodies dRVVT) and aCL antibodies Hyperprothrombinemia Prothrombin genotyping Hyperhomocysteinemia HPLC, FPIA (b) Factor VIII Activity (clotting or amidolytic) or antigen measurement (a) Markers and types of assay listed here represent the authors' choice.