factor V

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Related to Factor va: proaccelerin, Tissue factor, Factor viiia

factor V

[′fak·tər ′fīv]
(biochemistry)
References in periodicals archive ?
Use of a generally applicable tissue factor-dependent factor V assay to detect activated protein C-resistant factor Va in patients receiving warfarin and in patients with a lupus anticoagulant.
Analytical studies demonstrate the current manufacturing process' capability to remove significant amounts of extraneous proteins, and result in a reduction of Factor Va light chain content levels below the limit of detection of semi-quantitative Western Blot assay (<92 ng/mL, when reconstituted as directed).
The effect of this pathway is the inactivation of factor Va by activated protein C, a key reaction in shutting down thrombin formation and thus clot formation.
These antibodies in APS are believed to increase blood-clot formation by interfering with the natural breakdown of a blood component - Factor Va - that accelerates clotting.