amyloid

(redirected from Familial amyloidotic polyneuropathy)
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amyloid

[′am·ə‚lȯid]
(pathology)
An abnormal protein deposited in tissues, formed from the infiltration of an unknown substance, probably a carbohydrate.
References in periodicals archive ?
Long-term results of liver transplantation in familial amyloidotic polyneuropathy type I.
Nasdaq: ALNY), a leading RNAi therapeutics company, today announced that The Committee for Orphan Medicinal Products (COMP) within the European Medicines Agency (EMA) adopted a positive opinion for ALN-TTR01 designation as an orphan medicinal product for the treatment of familial amyloidotic polyneuropathy (FAP), one of the predominant forms of transthyretin (TTR)-mediated amyloidosis (ATTR).
ALN-TTR01 is a systemically delivered RNAi therapeutic being developed for the treatment of ATTR, including familial amyloidotic polyneuropathy (FAP) and familial amyloidotic cardiomyopathy (FAC).
Alnylam is developing ALN-TTR, a systemically delivered RNAi therapeutic targeting the TTR gene for the treatment of ATTR, including familial amyloidotic polyneuropathy (FAP) and familial amyloidotic cardiomyopathy (FAC).

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