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Fanconi's anemia |
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Fanconi's anemia [′fäŋ· kō·nēz ə′nē·myə] (medicine) An infantile anemia that resembles pernicious anemia; related to excessive chromosomal breakage and associated with the risk of developing leukemia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| in Northridge to find a bone marrow match to help a 13-year-old Valencia boy with Fanconi anemia. Children born with Fanconi anemia die young unless they receive healthy, transplanted, blood-producing stem cells. An extensive body of evidence has demonstrated the sensitivity of Fanconi anemia (FA) cells to redox-active xenobiotics, such as mitomycin C, diepoxybutane, cisplatin, and 8-methoxypsoralen plus ultraviolet irradiation, with toxicity mechanisms that are consistent with a deficiency of FA cells in coping with oxidative stress. |
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