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Insomnia
(redirected from Fatal familial insomnia)

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insomnia, abnormal wakefulness or inability to sleep sleep, resting state in which an individual becomes relatively quiescent and relatively unaware of the environment. During sleep, which is in part a period of rest and relaxation, most physiological functions such as body temperature, blood pressure, and rate of
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. The condition may result from illness or physical discomfort, or it may be caused by stimulants such as coffee or drugs. However, frequently some psychological factor, such as worry or tension, is the cause. Mild insomnia may often be relieved by a soothing activity like reading or listening to soft music. Chronic or severe insomnia requires treatment of the underlying physical or psychological disorder. In a few, very rare cases, individuals in certain families are subject to an incurable inherited insomia caused by prions that form plaques in the thalamus thalamus , mass of nerve cells centrally located in the brain just below the cerebrum and resembling a large egg in size and shape. The thalamus is a routing station for all incoming sensory impulses except those of smell, transmitting them to higher (cerebral) nerve
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; the disease appears suddenly in adulthood and ultimately is fatal.

Many patients respond to the assurance that their sleeplessness is a result of normal anxieties or a treatable physical disorder. Opportunities to ventilate anxieties often ease distress and helps resume normal sleeping patterns. Elderly persons are encourage to exercise more during the day; instructed relaxation, administration of tryptophan, and intake of warm milk helps some patients sleep. Sedatives and hypnotics drugs may be employed if the sleeplessness is impairing the subject's sense of well being. Those who wake because of pain receive an analgesic at bedtime; for those who experience insomnia accompanied with depression, an antidepressant often suffices.


insomnia

Inability to sleep adequately. The causes may include poor sleeping conditions, circulatory or brain disorders, breathing disorders (e.g., sleep apnea), mental distress (e.g., tension or depression), or physical discomfort. Mild insomnia may be treated by improving sleeping conditions or through traditional remedies such as warm baths, milk, or systematic relaxation. Apnea and its associated insomnia may be treated surgically or mechanically with breathing apparatus. Severe or chronic insomnia may necessitate the temporary use of barbiturates or tranquilizers, but such drugs are often addictive and may be decreasingly effective as the body builds up tolerance. Other methods of treatment include psychotherapy and hypnosis.


insomnia
The inability to sleep. If you suffer from it, the solution is to look up all the terms under "standards" in this encyclopedia. Dozing should occur shortly. If that does not work... well, at least you will become the computer guru on your block!
insomnia [in′säm·nē·ə]
(medicine)
Sleeplessness; disturbed sleep; prolonged inability to sleep.

Insomnia 

(also agrypnia), disturbed sleep. Insomnia manifests itself as a shortening of the period of nocturnal sleep, delay in onset of sleep, early awakening, and repeated interruption of sleep during the night. Sleep is also impaired qualitatively; it becomes more superficial, the length of deep sleep is diminished, and the balance between dream-sleep and dreamless sleep is upset. Insomnia occurs in cases of neurosis, certain cardiovascular and psychological illnesses, neuro infections, and injury to those parts of the brain that regulate the correct alternation of sleep and wakefulness. In healthy people, it may occur after great physical or mental stress, fatigue, strong emotional experiences, and similar instances. The total absence of nocturnal or daytime sleep for long durations almost never occurs.

Treatment involves adherence to the correct regimen of work and rest, the elimination of irritating factors, bathing, and exercise. The patient may be prescribed tranquilizers and, in cases of persistent insomnia, soporifics. In cases of insomnia caused by illness, treatment consists in eliminating the original illness responsible for the insomnia.

REFERENCES

Pervov, L. G. Son i ego narushenie, Moscow, 1965.
Fedotov, D. D. Son i ego rasstroistvo. Moscow, 1966.

V. S. ROTENBERG



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Other human TSEs include kuru, fatal familial insomnia (FFI), and Gerstmann-Straussler-Scheinker disease (GSS).
And most extreme and ghastly of all, as with the rare genetic disorder fatal familial insomnia, a patient who cannot sleep at all will die.
Prion diseases can be inherited, as in fatal familial insomnia (the Italian family that couldn't sleep): they include other fatal neurological disorders such as Mad Cow and scrapies.
 
 
 
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