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fatty |
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fatty 1. containing, consisting of, or derived from fat 2. (esp of tissues, organs, etc.) characterized by the excessive accumulation of fat How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| The latter enzyme was shown to be fatty acid synthase (FAS), which had earlier been strongly linked to tumor progression, making it an attractive therapeutic target. In hepatocytes, insulin stimulates a rapid increase in transcription of the gene coding for sterol response-binding protein-lc, which has been implicated in the expression of lipogenic genes; moreover, cholesterol synthesis genes in hepatocytes include fatty acid synthase (Fasn), steroyl-coenzyme A desaturase (Scd1), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Hmgcr), glucokinase (Gk), and farnesyl diphosphate synthase (Fdps) (Yeagley et al. |
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