11) announced the discovery of ferredoxin (Fd), a small iron-sulfur (FeS) protein of low redox potential, from Clostridium pasteurianum, and demonstrated it to be a physiological electron carrier for clostridial hydrogenase (reaction 1).
2002) Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation.
Evidence for lateral transfer of genes encoding
ferredoxins, nitroreductases, NADN oxidase, and alcohol dehydrogenase 3 from anaerobic prokaryotes to Giardia lamblia and Entamoeba histolytica.
Role for
ferredoxins in the origin of life and biological evolution.
The evolution of prokaryotic
ferredoxins - with a general method for correcting for unobserved substitutions with less branched lineages.
The lecture proceeds with a discussion of the various structures of the iron and copper proteins involved (cytochromes,
ferredoxins and plastocyanins) and shows that we currently know rather less about the manganese site implicated in the water-splitting step.
Evidence for lateral transfer of genes encoding
ferredoxins, nitroreductases, NADH oxidase and alcohol dehydrogenase 3 from anaerobic prokaryotes to Giardia lamblia and Entainoeba histolytica.