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the treatment of various disorders by the artificial inducement of high body temperature. Fever is induced by various methods, including the introduction into the body of a foreign protein, the causative agents of certain diseases (malaria), or chemical substances (Pyrogenal, suspensions of sulfur in oil). Fever therapy activates blood circulation, metabolism, and the immunobiologic reactions of the body. Such therapy is used only rarely—in treating some forms of dermatitis, syphilis, and schizophrenia. Fever therapy should not be used to treat malignant tumors, hypertension, blood diseases, thyrotoxicosis, and a number of other disorders.