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thrombolytic drug
(redirected from Fibrinolytics)

   Also found in: Wikipedia 0.02 sec.
thrombolytic drug (thrŏm'bəlĭt`ĭk) or clot-dissolving drug, substance, such as streptokinase or tissue plasminogen activator (tPA), that causes the breakdown of blood clots (see thrombosis thrombosis (thrŏmbō`sĭs), obstruction of an artery or vein by a blood clot (thrombus).
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) that obstruct the flow of blood through the vessels. Its uses include injection during or shortly after a heart attack or stroke stroke, destruction of brain tissue as a result of intracerebral hemorrhage or infarction caused by thrombosis (clotting) or embolus (obstruction in a blood vessel caused by clotted blood or other foreign matter circulating in the bloodstream); formerly called
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 (see infarction myocardial infarction or heart attack is usually caused by a blockage in one of the coronary arteries that supply blood to the heart muscle. The blockage typically occurs when a blood clot (see thrombosis ) lodges in an area already narrowed by arteriosclerosis ; other
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) to prevent clots from blocking blood flow to the heart muscle or brain.


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Passage of many or large clots indicates that you have passed more blood than the fibrinolytics can work on, and you are probably bleeding to excess.
Previous studies of full-dose fibrinolytics have reported that less than 80 percent of patients achieved some restoration of blood flow through blocked arteries at 60 minutes.
Through this partnership, which will broadly promote the most widely-used GP IIb-IIIa inhibitor and the leading fibrinolytics franchise in the U.
 
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