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fibrosis
(redirected from Fibrogenesis)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
fibrosis
the formation of an abnormal amount of fibrous tissue in an organ or part as the result of inflammation, irritation, or healing

fibrosis [fī′brō·səs]
(medicine)
Growth of fibrous connective tissue in an organ or part in excess of that naturally present.


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Discussion Several serum markers have been developed to assess fibrogenesis and investigations have been made to replace liver biopsy with non-invasive markers of liver fibrosis, which have been assessed in many studies.
Others discuss the molecular and physiological aspects of the angiotensin IV-ondulain regulated aminopeptidase interaction, its regulatory effects on cellular function, its biochemical and physiological actions and role in the treatment of cardiovascular diseases, its effects in renal fibrogenesis, the role of vitamin D in the modulation of the pancreatic rennin-angiotensin system, and pharmacotherapeutic effects of angiotensin II type 1 receptor blockers.
Since, TNF-[alpha] is one of the earliest events in hepatic inflammation, triggering a cascade of other cytokines that co-operate to kill hepatocytes, recruit inflammatory cells and initiate a wound healing response that includes fibrogenesis.
 
 
 
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