first filial generation

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first filial generation [¦fərst ¦fil·ē·əl jen·ə′rā·shən]

(genetics)

The first generation resulting from a cross between parents homozygous for different alleles at a locus; all members are heterozygous at the locus. Symbolized F₁.

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F1
F2

filial
Mendelism

No developmental abnormalities have been observed in first filial generation (F1) male or female offspring resulting from mating finasteride-treated male rats (80 mg/kg/day; 61 times the human exposure) with untreated females.

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