Francois Magendie


Also found in: Medical.

Magendie, François

(fräNswä` mäzhäNdē`), 1783–1855, French physician. He taught at the Collège de France and is considered a founder of experimental physiology. He distinguished the motor and sensory portions of peripheral nerves and studied the function of veins, the effect of air in arteries, and the uses and effects of various drugs.

Magendie, François

 

Born Oct. 6, 1783, in Bordeaux; died Oct. 7, 1855, in Sannois, department of Seine-et-Oise (according to other data, Oct. 8, 1855, in Paris). French physiologist. Member of the Paris Academy of Sciences (1821; vice-president, 1836) and the Medical Academy (1819).

Magendie was one of the first to use the experimental method in animal physiology. (This approach was carried on by his pupil, C. Bernard). The best known of Magendie’s works deal with the physiology of the nervous system. In 1822 he proved experimentally that the anterior roots of the spinal cord are efferent (motor) and that the posterior roots are afferent (sensory). This is known as the Bell-Magendie law. Magendie did research on the trophic influence of the trigeminal nerve on eye tissue, the sensitivity of the cerebral cortex to pain stimuli, the significance of subcortical nerve centers in the coordination of movement, and the properties of cerebrospinal fluid. He also studied the mechanisms of the digestive tract and described the act of vomiting.

WORKS

Précis élémentaire de physiologie, 3rd ed., vols. 1-2. Paris, 1833.

REFERENCE

Karlik, L. N. “Fransua Mazhandi.” Klinicheskaia meditsina, 1959, vol. 37, no. 2.
References in periodicals archive ?
Some wellknown nineteenth-century practitioners active in France include Julien Legallois (1770-1814), Pierre-Hubert Nysten (1771-1818), Guillaume Dupuytren (1777-1835), Nicola Blondlot (1808-1877), Achille Longet (1811-1871), Francois Magendie (1783-1855), Jean Pierre Flourens (1794-1867), Claude Bernard (1813-1878), Louis Pasteur (1822-1895), Paul Bert (1833-1886) and the Russian-French Elias von Cyon (1843-1912).
Cabe recordar a figuras como Francois Magendie (1783-1855), quien estudio los mecanismos de toxicidad de la emetina, estricnina y cianuro; a su estudiante, Claude Bernard (1813-1878), quien hizo contribuciones a la comprension de la intoxicacion por monoxido y curare, y a Rudolf Kobert (1854-1918), quien estudio el digital y los alcaloides del ergot (6).
Nineteenth-century practitioners of experimental physiology such as Francois Magendie and Claude Bernard were fond of using it to describe the work of their predecessors, although long before that Moliere had one of his characters in Le Malade imaginaire apply it to the explanations that physicians offered for the virtues of their therapies.
Francois Magendie (17831855) had obtained his medical degree from Universite de Paris in 1808.
Full browser ?