GTP-binding protein


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GTP-binding protein

[¦jē‚tē¦pē ′bīn·diŋ ‚prō‚tēn]
(cell and molecular biology)
One of a large family of heterotrimeric or monomeric proteins that bind GTP (guanosine 5′-triphosphate) as intermediaries in intracellular signaling pathways. Also known as G protein.
References in periodicals archive ?
Vesicle endocytosis requires GTP hydrolysis by the GTP-binding protein dynamin, which participate in fission of the nerve terminal plasma membrane to reform vesicles.
Ephedra monosperma had mostly degradome proteins (profilins, desiccation-related protein, the GTP-binding protein RAN-1, and ceramidase) and had only two secretome proteins that we could detect in this initial comparative study--serine carboxypeptidase and glucan endo-1,3-[beta]-glucosidase.
CgtA is a highly conserved essential GTP-binding protein, coded by the cgtA gene, belonging to Obg subfamily in prokaryotes (8).
164) includes rhodopsin, the pigment that absorbs light; GTP-binding protein, or transducin; an enzyme called rhodopsin kinase; another called S-antigen; and a retinoid-(vitamin A-) binding protein.
1982) Functional reconstitution of beta-adrenergic receptors and the stimulatory GTP-binding protein of adenylate cyclase.
An interesting phenomenon was that some proteins that are associated with cell growth, proliferation, differentiation, apoptosis, and death Isomatotropin, developmentally regulated GTP-binding protein 2, insulin-like growth factor binding, ATP-binding protein associated with cell differentiation, and interleukin-1[beta]-converting enzyme (ICE)-like apoptotic protease 5 [Fas-associating protein with Death Domain (MORT1)associated Caenorhabditis elegans cell death gene (CED-3) homolog] were correlated with age.
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho.
Characterization as a glycoprotein interacting with a GTP-binding protein.
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins.
The P-loop--a common motif in ATP and GTP-binding proteins Trends Biochem.
In large part, the anti-inflammatory actions of statins result from the depletion of two biologically important cholesterol pathway intermediates, farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP), which are required for posttranslational modification of small GTP-binding proteins (small GTPases) such as Ras (FPP) or Rac and Rho (GGPP) (Figure 3).
Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go.