GTPase


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GTPase

[′jē‚tē¦pās]
(cell and molecular biology)
One of a family of monomeric GTP-binding proteins.
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06649 SNP ID Gene * Description BIEC2_577013 RALGAPA2 Ral GTPase activating protein, alpha subunit 2 BIEC2_579415 KIF16B Kinesin family member 16B BIEC2_580028 MACROD2 MACRO domain containing 2 BIEC2_580291 MACROD2 MACRO domain containing 2 BIEC2_580790 SPTLC3 Serine palmitoyltransferase, long chain base subunit 3 BIEC2_600400 AK128005 BIEC2 600504 PPP4R1L Protein phosphatase 4, regulatory subunit 1-like BIEC2_600563 STX16 Syntaxin 16 BIEC2_600572 STX16 Syntaxin 16 BIEC2_600582 GNAL Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide SNP, single nucleotide polymorphism; MAF, minor allele frequency.
KRAS is a member of the ras gene family and encodes for a GTPase protein involved in multiple signal transduction pathways.
falciparum GTPase TetQ gene (PfTetQ, PFL1710c) are associated with reduced susceptibility to doxycycline (9); this association was later confirmed (7).
The reason for this fluctuation may be that NTF2 and small GTPase Ran are involved not only in the 20E signal transduction pathway but also in the nucleo-cytoplasm transport of macromolecules (He et al.
519 AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.
The researchers discovered that the two targets are Rac GTPase and Pak (p21-activated kinase).
Multistate GTPase control co-translational protein targeting.
65 fucosyltransferase, myeloid-specific) RND2 Rho family GTPase 2 -0.
To do this we will perform a genetic screen looking for external modification of the gain of function phenotype of the small GTPase Racl (in which polarity is affected).
Additionally, clinical molecular tests for serine/threonine-protein kinase B-Raf (BRAF) and GTPase Kras (KRAS) gene biomarkers, as well as for epidermal growth factor receptor (EGFR), are driving the demand for the FFPE sample preps.
Increased intracellular calcium can activate the ras oncogene by producing GTPase inhibition and magnesium deficiency related phosphorylation defects can inactivate the tumour suppressor genes.