An increase in theta power is related to an increase in theta in the hippocampus, known to be an inhibitory rhythm associated with GABAergic
activity (Klimesch et al.
system has been widely demonstrated to regulate cognitive function (Menzies et al.
Numerous studies have established that acute and chronic behavioral effects of alcohol are differentially mediated through GABAergic
receptor subunits (for a review, see Grobin et al.
, glutamatergic, monoamine and NO systems (Adachi et al.
modulators: late-stage drug analysis and forecasts
Their binding to the allosteric site of the receptors enhances the affinity of the GABA-binding site for GABA, which results in an enhancement of chloride influx and facilitates the GABAergic
transmission (Olsen 1981; Ticku and Maksay 1983).
Cyclosporin also neuroprotects against the slow brain degenerations of the vulnerable neuron populations seen in animal models of Alzheimer's disease (protects septal cholinergic neurons), Parkinson's disease (preserves substantia nigra dopaminergic neurons), Huntington's disease (retains striatal GABAergic
interneurons) and amyotrophic lateral sclerosis (slows the loss of motor neurons in the spinal cord).
Other neurotransmitter systems may also be affected by exposure to Ginkgo biloba including adrenergic, dopaminergic, serotonergic, glutamatergic, and GABAergic
systems (reviewed by Ahlemeyer and Krieglstein, 2003).
Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: involvement of the GABAergic
and opioids systems.
These cells are referred to as GABAergic
neurons as they use the chemical messenger gamma-amino butyric acid (GABA).
In an attempt to uncover a common site of cellular action for abused substances, the authors focused on the GABAergic
system, a critical modulator of local synaptic activity in the CeA, a brain region considered to be a key element of the brain reward system.
The nondopaminergic neuronal subpopulation in these regions includes GABAergic
(Deniau et al.