Gamma-Aminobutyric Acid

(redirected from Gamma Hydroxy Butyrate)
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Gamma-Aminobutyric Acid

 

NH2CH2CH2CH2COOH, an acid formed by the decarboxylation of glutaminic acid under the action of the enzyme decarboxylase. In the body, metabolism of gamma-aminobutyric acid gives succinic acid, which participates in the tricarboxylic acid cycle. Free gamma-aminobutyric acid is found in many plants. In higher mammals gamma-aminobutyric acid is only found in the brain, where its concentration reaches 100 mg percent. Gamma-aminobutyric acid is assumed to exert a retarding action on nerve activity, which is apparently associated with its effect on the permeability of biological membranes.

References in periodicals archive ?
Other scenes from the dance floor this past summer included: one man's dying and two of his friends' going into convulsions after overdosing on the drug gamma hydroxy butyrate, also referred to as GHB, at a bar on New York's Fire Island the weekend of the Morning Party, the annual Gay Men's Health Crisis fund-raiser; and the Atlanta police's shutting down one night of the Hotlanta dance weekend after three men were rushed to the hospital for GHB-related emergencies.
She testified she willingly drank a shot glass of gamma hydroxy butyrate, which she later learned was the so-called date-rape drug, that Luster poured it for her at his Mussel Shoals home and that she blacked out.
The 35-year-old man overdosed on the drug gamma hydroxy butyrate and died in the Fire Island Pines in the early-morning hours of Sunday, August 16.
The woman told police that Luster assaulted her repeatedly at his home, and admitted he had given her Liquid X - a slang term for gamma hydroxy butyrate - which leaves victims unable to fend off an attack and affects their ability to recall events.
In August the complaints took on a new urgency when one man died of an overdose of the drug gamma hydroxy butyrate (GHB) the evening before the party and 21 revelers were arrested at the festivities for drug possession.
On Friday, a University of California, Santa Barbara, student, whose memory of her alleged sexual assault led to Luster's arrest, testified she didn't give consent to the encounter and was drugged by the so-called date rape drug gamma hydroxy butyrate, or GHB.
Drugs such as rohypnol, a central nervous system depressant, and gamma hydroxy butyrate, an anesthetic that can scramble the memory, are being used more often, said Michele Mittelman, a coordinator for the Sexual Assault Response Team, a coalition of law enforcement and health agencies.
I knew Frank Giordano, who died August 16 of a of gamma hydroxy butyrate (GHB) overdose on Fire Island, N.
Carpenter said the east county is seeing the same kind of drugs found in the west, primarily methamphetamine, followed by marijuana, cocaine and the newer date-rape drugs, such as rohyphynol and gamma hydroxy butyrate.
A depressant passed around at parties in liquid form, gamma hydroxy butyrate (GHB) has earned the street name ``great bodily harm'' but has still become increasingly popular, owing in part to the widespread dissemination of its recipe on the Internet, according to LAPD Detective Trinka Porrata.