gap junction

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gap junction

[′gap ‚jəŋk·shən]
(neuroscience)
An intercellular junction composed of cylindrical channels connecting adjacent cells; considered to be a low-resistance pathway for intercellular communication. Also known as communicating junction; nexus.
References in periodicals archive ?
Gap junctions, made up of connexons; sustain the integral function of cells by permitting communication between them.
It has been shown that retinal gap junctions (40,41) contribute to the neural noise reduction that is mediated by signal transmission far beyond each classical RF.
be/CMTMutations/) that encodes connexin 32 (CX32), a myelin-related protein in the peripheral nervous system (PNS) and central nervous system (CNS) that is considered to form gap junctions (GJs) that shorten the diffusion pathway of ions and small molecules between cells.
12-25 The hexameric Cx43 protein complex connexon, both as a gap junction and as a hemichannel, forms large-conductance ion channel with chemical gating similar to the Bcl-2 channels.
Connexins, the major proteins of gap junctions, are expressed in various cell types and are important in the key process of intercellular communication.
Beyer, "Oxidative stress, lens gap junctions, and cataracts," Antioxidants and Redox Signaling, vol.
Contact between granulosa cells with oocytes through gap junctions to inhibit oocyte maturation by inhibiting the meiotic process.
7 The actions of progesterone on pregnant mymetrium include relaxation of myometrial smooth muscle, blocking of the action of oxytocin and inhibition of the formation of gap junction.
Martin AO, Mathieu MN, Chevillard C, Guerineaux N (2001) Gap junctions mediate electrical signaling and ensuing cytosolic Ca2+ increases between chromaffine cells in adrenal slices: a role in catecholamine release.
Citation: "Formation of functional gap junctions in amniotic fluid-derived stem cells induced by transmembrane co-culture with neonatal rat cardiomyocytes"; Jennifer Petsche Connell et al.
In general, the exchange of information between the billions of neurons that make up the neuronal forest takes place through two types of highly specialised structures: chemical synapses (the majority) and so-called gap junctions (a substrate of one class of electrical synapse).
However, researchers from the University of Bristol's School of Biochemistry in collaboration with a team from the University of Bath, have shown that the very first trigger in this process is a flash of calcium which spreads like a wave back from the wound edge through gap junctions that connect all the cells.