Gastrin


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Related to Gastrin: enterogastrone, somatostatin, secretin

gastrin

[′gas·trən]
(biochemistry)
A polypeptide hormone secreted by the pyloric mucosa which stimulates the pancreas to release pancreatic fluid and the stomach to release gastric acid.

Gastrin

 

a polypeptide hormone secreted by the mucous membrane of the pylorus of the stomach; it is secreted when the pylorus is stretched or acted on by chemical stimulants (for example, products of the decomposition of food) or impulses from the vagus nerves. Gastrin increases the secretion of gastric and pancreatic juices, as well as of bile, and alters the tone and motility of the stomach and intestines. An increase in the hydrochloric-acid content of the pylorus (when acidic gastric juice enters it) inhibits the secretion of gastrin. Two kinds of gastrin, which are very similar in structure and physiological properties, have been distinguished. Gastrin has been synthesized chemically.

References in periodicals archive ?
Atrial Natriuretic Peptide (ANP), mainly secreted by atrial cardiomyocytes, participates in cardiovascular regulation, sodium resorption and additionally modulates gastric peristalsis and regulates gastric acid secretion by affecting the release of somatostatin and gastrin [30, 31].
Serum gastrin concentration and changes in G and D cell densities in gastric antrum in children with chronic gastritis.
Nine of 62 patients (15%) had serum testing for gastrin, insulin, glucagon, and/or vasoactive intestinal peptide, and in no cases were these abnormally elevated.
1987) Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.
Blood was centrifuged at 3000 rpm for 10 min and the supernatant was used for determination of gastrin levels using a Rat Gastrin ELISA kit, following the manufacturer's instructions.
This case did not have any evidence of gastric ulcer, the serum gastrin was normal.
Today, the picture is changed: Peptic ulcer is caused by Helicobacter pylori infection and does not need gastrin measurement for diagnosis.
In dogs received continuous jejunal interposition, postoperative serum gastrin level was significantly lower than before surgery either in fasting or postprandial (p<0.
Significant negative correlations were recorded between the plasma concentrations of CCK, secretin, gastrin and pregastric esterase activity of the contents (p<0.
Further blood samples were taken before study commencement and after intervention to measure serum levels of gastrin, motilin and PP.
Additional RISH probes under development include alpha-fetoprotein, calcitonin, cytomegalovirus, gastrin, insulin, pancreatic peptide, and more.
This work aimed to analyze the regional distribution and relative frequency of immunoreactive (IR) endocrine cells to serotonin, gastrin, CCK and enteroglucagon in the gastric mucosa and intestine mucosa of Phyllostomidae Lonchorhina aurita (Thomes, 1901) and Molossidae Molossus molossus (Wagner, 1843), both insectivorous bats, using immunohistochemistry.