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gene targeting |
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gene targeting [′jēn ‚tär·gəd·iŋ] (genetics) Replacement, by genetic engineering and homologous recombination, of a mutant (or wild-type) gene by a wild-type (or mutant) copy that may also contain a reporter gene. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| New frontiers in gene targeting and cloning: success, application and challenges in domestic animals and human embryonic stem cells. In their new experiment, Capecchi and Chisaka used a method called gene targeting to insert into mice embryos two copies of a mutant homeobox gene, called Hox-1. As part of this effort a novel gene targeting system was developed and published in Nature Genetics in June 2004. |
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