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general paralysis

   Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia 0.01 sec.
general paralysis [¦jen·rəl pə′ral·ə·səs]
(medicine)
A chronic, progressive form of syphilis caused by inflammatory and degenerative changes in the brain and meninges and characterized by physical, emotional, and intellectual deterioration; occurs at least 10 to 15 years after initial infection.


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85 RC450 General Paralysis of the Insane or GPI, is the term used specifically for the tertiary form of syphilis in which both a physical and mental deterioration takes place.
It resulted in huge financial loss and general paralysis of the railway system.
This pattern was familiar to psychiatrists of the period: as one explained, "[i]f you exclude general paralysis and alcoholism, women are more predisposed to madness than men.
 
 
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