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Epistasis
(redirected from Genetic interaction)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
epistasis [ə′pis·tə·səs]
(genetics)
The suppression of the effect of one gene by another.
(medicine)
A checking or stoppage of a hemorrhage or other discharge.
(pathology)
A scum or film of substance floating on the surface of urine.

Epistasis 

the interaction of two nonallelic genes (that is, genes that are at different loci) whereby one of them, called the epistatic gene, suppresses the effect of the other one, called the hypostatic gene. Phenotypically, epistasis is manifested as a deviation from the segregation that would be expected in digenetic inheritance; in this case, however, there is no violation of Mendel’s laws, inasmuch as the alleles of the interacting genes are distributed in complete conformity to the law of independent assortment, or combination.



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And even the contribution from genes alone is often perplexingly complicated, as networks of genetic interactions encompassing hundreds of genes underlie many common diseases.
A Macquarie University biologist, Sarah Pryke, said there was no chemical or genetic interaction between the parents at work.
If no particular family or set of families dominates the population, the effects of any genetic interaction will be minimized.
 
 
 
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