Epistasis

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Related to Genetic interaction: epistasis

epistasis

[ə′pis·tə·səs]
(genetics)
The suppression of the effect of one gene by another.
(medicine)
A checking or stoppage of a hemorrhage or other discharge.
(pathology)
A scum or film of substance floating on the surface of urine.

Epistasis

 

the interaction of two nonallelic genes (that is, genes that are at different loci) whereby one of them, called the epistatic gene, suppresses the effect of the other one, called the hypostatic gene. Phenotypically, epistasis is manifested as a deviation from the segregation that would be expected in digenetic inheritance; in this case, however, there is no violation of Mendel’s laws, inasmuch as the alleles of the interacting genes are distributed in complete conformity to the law of independent assortment, or combination.

References in periodicals archive ?
Statistical modeling of genetic interaction becomes quite difficult as the number of genetic loci is increased.
Taken together, the data suggest that wild-cultured genetic interactions have the potential to occur when geoduck farming operations are near wild populations.
This study was the first to assess genetic interactions with dioxin exposure, to our knowledge.
GENETIC INTERACTIONS BETWEEN THE G1 CYCLIN CLN3 AND TH173 MAY LINK THE ENDOPLASMIC RETICULUM TO REGULATED CELL DIVISION.
Increasingly, it is thought that PCOS is caused by a number of underlying genetic interactions and predispositions and that environmental issues--including diet, exercise, pollution, and stress--play an important role in PCOS' development.
The complexity of genetic interactions, the effects of disease, and other environmental factors complicate the interpretation of pharmacogenetic results.
Genetic Interactions of the Saccharomyces Cerevisiae Kin3 Gene
Aside from slightly below average birth weights, the CD-1 showed no malformations, suggesting distinct ethanol and genetic interactions in the B6 strain that is not common to this outbred strain.
Researchers have tried to simulate crop-pathogen genetic interactions with computer-based models.
Nadeau pioneered the harnessing of informatics to better understand and predict genetic interactions.
Genetic interactions between hsp70-1shou5 and other cellulose related mutants will be examined.
This overview of seed biology covers the development and regulatory process from the developing seed to dormancy to germination and seedling growth, keeping in mind the complex environmental, physiological, molecular and genetic interactions that occur throughout the cycle.