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In DN patients, the relative abundance of the glycopatterns of ([sz]-1,4)-linked GlcNAc recognized by lectin DSA was higher than the others.
As a result of these enzymatic processes, a GlcNAc unit can be added in a defined way to the non-reducing end of the starting oligosaccharide without accompanying self-coupling reactions.
Indeed, they found that if they added glucose to nerve cells in petri dishes, the level of proteins with the GlcNAc addition increased in proportion to the amount of glucose in the dishes.
Because lectin-mediated processes can be inhibited by low-molecular weight sugars (reviewed by Lis and Sharon ), the effect of GlcNAc (Wako Pure Chemical Co.
Since there were ~26 mM GlcNAc sites in the HA, a ~5 mM "saturation" in [Cu(II)] might indicate a ~20% GlcNAc-binding by Cu(II) for a maximal effect.
Extensions of Asn-linked GlcNAc may be L-Fuc in ([alpha]1-6) and/or ([alpha]1-3) linkage.
Scanning the available Dictyostelium discoideum proteome for O- linked GlcNAc glycosylation sites using neural networks.
Now chemists at the California Institute of Technology (Caltech) have shown for the first time that a specific sugar, known as GlcNAc ("glick-nack"), plays a key role in keeping the cancerous monsters "fed.
1] solutions of GlcNAc, fucose, galactose, or PW for 10 min prior to insemination.
Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: Their functions and target proteins.
The GlycA NMR signal is chemically nonspecific in origin, coming from the N-acetyl methyl groups of GlcNAc residues on the antennary branches of serum glycoproteins (9).
Donor sugars for UGT76E1 are UDP glucose, UDP GlcNAc and UDP5S glucose, respectively (Yang et al.
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