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glucocerebrosidase

   Also found in: Medical, Wikipedia 0.01 sec.
glucocerebrosidase [‚glü·kō‚ser·ə′bräs·i‚dās]
(biochemistry)
An enzyme that removes the glucose from glycosyl ceramide and is defective or missing in Gaucher's disease.
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Food and Drug Administration (FDA) for prGCD, the company's proprietary plant-cell expressed recombinant form of glucocerebrosidase (GCD) for the treatment of Gaucher disease.
PROTALIX GETS FDA FAST TRACK DESIGNATION FOR PRGCD by Worldwide Biotech
Gaucher disease, the most commonly diagnosed lysosomal storage disorder, is caused by inherited genetic mutations in the GBA gene, which result in deficient activity of the enzyme acid beta-glucosidase, also known as glucocerebrosidase (GCase).
Amicus and Shire enter Into $440 million ex-US licensing agreement to ... by BIOTECH Patent News
[3,4] Clinical features of splenomegaly and an abnormal glucocerebrosidase level are diagnostic.
Retroperitoneal Soft Tissue Mass Presenting With Acute Renal Failure by Bertram, Heidi C.; Watkin, William G. / Archives of Pathology & Laboratory Medicine
 
 
 
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