glucocorticoid

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glucocorticoid

[¦glü·kō¦kȯrd·ə‚kȯid]
(biochemistry)
A corticoid that affects glucose metabolism; secreted principally by the adrenal cortex.
References in periodicals archive ?
WADA reported in 2011 that all glucocorticosteroid AAFs were synthetic drugs, with budesonide the most prevalent.
McEwen asserted that if glucocorticosteroid secretion
Antibiotic and oral glucocorticosteroid prescriptions for chronic treatment were excluded (according to dosage schedule [greater than] 14 days).
Hyperglycemia normally occurs within minutes of severe TBI as part of the sympatho-adrenal stress response[3,43] and may be a proxy indicator for injury severity in humans,[11,48] Particularly in the setting of ischemia, it aggravates injury by driving anaerobic metabolism, enhancing increased glycolysation of membrane molecules, IC acidification, free radical formation, blood flow alterations and other effects,[11,43,48,65] Glucocorticosteroid use after injury amplifies the metabolic response, notably increased gluconeogenesis; proteolysis and lipolysis for gluconeogenesis, peripheral insulin resistance, hyperglycemia and subsequent osmotic diuresis.
In our pivotal clinical studies, three times more patients achieved clinical remission and mucosal healing with UCERIS compared with patients taking placebo, and no clinically significant differences in glucocorticosteroid side effects were seen versus placebo after eight weeks of treatment.
an established, locally-acting glucocorticosteroid, indicated for the treatment of inflammatory bowel disease (IBD), from AstraZeneca
Invasive aspergillosis occurs as a result of three factors: (1) suppression of the immune response due to debilitating disease or therapy with cytotoxic drugs or radiation therapy, (4,8,13) (2) glucocorticosteroid therapy with the resultant diminished inflammatory response and disruption of the normal flora by antimicrobial agents, (13,14) and (3) local implantation of the fungus.
The companies have signed a right of first refusal regarding OTC rights for Rhinocort Aqua, a pump spray containing the glucocorticosteroid budesonide, with a local anti-inflammatory effect for the treatment of non-infectious rhinitis (such as hay fever and house dust mite allergy).
In the authors' case series of 8 patients, the condition often worsened after glucocorticosteroid tapering or responded incompletely and required additional immunosuppressive agents for effective treatment.
Age and food deprivation affects expression of the glucocorticosteroid stress response in Magellanic Penguin (Spheniscus magellanicus) chicks.
acting beta agonist ("LABA") plus a glucocorticosteroid in an inhaler;
Following an analysis of the Appellant's A-Sample, the Doping Control Laboratory in Cologne reported an Adverse Analytical Finding to the FIS on 15 February 2005, stating that the sample contained the substance Dexamethason, a Prohibited Substance listed as a glucocorticosteroid in Group S9 on the 2005 Prohibited List (International Standard) of the World Anti-Doping Code (the "WADC").