In the much larger government-funded GAIT trial, 67 percent of the 317 people who took
glucosamine hydrochloride (1,500 mg a day) plus chondroitin (1,200 mg a day) reported less knee pain.
II-1-2 Flow Chart of
Glucosamine Hydrochloride Production
The study was developed as an extension of the GAIT (Glucosamine/Chondroitin Arthritis Intervention Trial) study, which showed that the combination of
glucosamine hydrochloride (1,500 mg/day) and chondroitin sulfate (1,200 mg/day) was effective in a moderate to severe subgroup of patients.
GAIT's lead investigator explains why the study used
glucosamine hydrochloride.
Other studies indicate that the glucosamine sulfate that's found in most supplements works better than the
glucosamine hydrochloride that was used in this study.
The article suggests that the study results should not be considered completely applicable because "the glucosamine formulation that was used,
glucosamine hydrochloride, is not the compound that is used in U.
GAIT was criticized for using
glucosamine hydrochloride instead of the more studied sulfate form.
Schiff(R) uses
Glucosamine Hydrochloride (HCl), which has the highest potency of active glucosamine among glucosamine forms.
Another concern that has been raised about the validity of the study's findings is that the glucosamine formulation that was used,
glucosamine hydrochloride, is not the compound that is used in U.
One of the outcomes of the study showed that the response rate to the combination of
glucosamine hydrochloride and chondroitin sulfate in those study participants with moderate to severe knee pain was 79.
It contains 1500 mg Regenasure
glucosamine hydrochloride (HC1); chondroitin (1200 mg); and calcium citrate malate (CCM), combining calcium, citric acid and malic acid, (30% Daily Value).
Available as both
Glucosamine Hydrochloride and Glucosamine Sulphate, Osamine(TM) brings forward high quality pharmaceutical grade glucosamine to the worldwide marketplace.
