When taken in unison with
glucosamine hydrochloride, chondroitin sulfate packs an even greater punch.
5%, 1%, 2%, 3%, and 30%) of
glucosamine hydrochloride solution (40 [micro]L) in water were also examined for antibacterial effect.
The six-month study involved 1,500 osteoarthritis patients who were given a placebo or daily doses of 1,500 mg of
glucosamine hydrochloride and/or 1,200 mg of chondroitin sulfate or 200 mg of the common prescription pain medication celecoxib.
The GAIT trial found that patients with severe knee pain randomized to take 1,500 mg
glucosamine hydrochloride had a more than 65 percent reduction in pain, but those taking a combination of glucosamine and 800 mg of chondroitin sulfate had an almost 80 percent reduction in pain.
Each day, participants took either three 500-milligram doses of
glucosamine hydrochloride, three 400-milligram doses of chondroitin sulfate, both doses of glucosamine and chondroitin together, 200 milligrams of celecoxib (Celebrex) or a placebo.
Subjects in this study were older adults with type 2 diabetes who were given supplements of 1,500 mg of
glucosamine hydrochloride in combination with 1,200 mg of chondroitin sulfate (Cosamin DS[R]) for 90 days.
Biocare's
Glucosamine Hydrochloride (0121-433 3727) will help build up cartilage between her discs and reduce pain.
For example, in October 2009, EFSA's panel concluded that "a cause and effect relationship has not been established between the consumption of
glucosamine hydrochloride and a reduced rate of cartilage degeneration in individuals without osteoarthritis"(Question number: EFSA-Q-2009-00412), Consequently, popular glucosamine supplements cannot make that claim on their packaging and in their promotion and advertising.
Navamedic, which focuses on the development and production of
glucosamine hydrochloride (HCl)-based drugs, is looking at around ten different projects.
Glucosamine, which is one of the most widely used products, showed mixed results, with glucosamine sulfate-the form most often tested in trials--scoring three out of five, and
glucosamine hydrochloride, which has a slightly different chemical structure, scoring one.
However, some experts point out that it used
glucosamine hydrochloride, while most people nowadays take glucosamine sulfate, which is said to be more bio-available.
For dogs the line includes three new products: Cosequin Hip & Joint Support Supplement with
glucosamine hydrochloride (HCI) and methylsulfonylmethane (MSM), Cosequin Hip & Joint Support Plus Supplement with Perna Canaliculus (Green Lipped) Mussel, and Cosequin Multi Total Joint Health and Protection with Multivitamins and Minerals.
