Kinetics of glycoxidation of bovine serum albumin by methylglyoxal and glyoxal
and its prevention by various compounds.
The latter may react with singlet oxygen to produce dioxetane 91 as a precursor of oxalic acid (HOOC-COOH), glycolaldehyde 92, and glyoxal
93, all of which are known products of glycoxidation .
Particularly, CML could be formed by the reaction of glucose and other sugars and glyoxal
with amino groups of arginine and lysine or by lipids peroxidation .
Further the property of gelatin film can improve by the chemical treatment, for example films reticulated with formaldehyde and glyoxal
have higher tensile strengths, opacity, lower water vapor permeability, and good color differences than the untreated films .
Antibacterial properties of honey are the result of the low water activity causing osmosis, chelation of free iron, its slow release of hydrogen peroxide, high acidity, and the antibacterial activity of methyl glyoxal
However, the commercially prepared reagents have different reactivities because different products or geometric isomers are formed from the addition of urea, formaldehyde and glyoxal
, methylglyoxal) and the free amino groups of amino acids, peptides and proteins .
Mark Henning, global general manager for Dow Microbial Control, commented that "During the past few years, formulators have increasingly made and sold products that are supposedly glutaraldehyde-based, but actually contain other ingredients, including formaldehyde and glyoxal
One of the most promising approaches to fighting cancer revolved around the Carbonyl group - Glyoxal
In addition to the pathway involving Amadori products, several AGEs are formed independently by direct binding of reactive carbonyl compounds (RCCs), including glyoxal
, methyglyoxal, and 3-deoxyglucosone (3DG), preferentially on arginine residues of proteins, generating hydroimidazolones as byproducts (6).
For instance, histochemical methods relying on the Karnovsky and Roots cholinesterase method to localize endplates (57) and the glyoxal
bis-(2 hydroxyanil) (GBHA) (58) or von Kossa (59) methods to localize [Ca.
NTB may result from the Maillard reaction, however in this case the amino acids react with nonsugar carbonyl compounds, such as diacetyl, glyoxal