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A discrete nodular lesion of inflammatory tissue in which granulation is significant.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

References in periodicals archive ?
Calikoglu E, Anadolu R, Bovyat A, Peksari Y: A case of generalized granuloma annulare.
Systematic review of 100 cases and comparison with localized granuloma annulare.
Piana S, Pizzigoni S, Tagliavini E, Serra S, Albertini G: Generalized granuloma annulare associated with scabies.
20) This suggests a possible link between herpes viral infection and the development of postherpetic granuloma annulare, particularly given the histologic finding of a perineurovascular and/or perifollicular lymphohistiocytic infiltrate with multinucleated giant cells in our cases.
In conclusion, we report the cases of 5 patients who developed granuloma annulare with multinucleated giant cells and a perineurovascular and/or perifollicular pattern of infiltrate at the site of prior herpes zoster.
Granuloma annulare in a site of healed herpes zoster: Wolf's isotopic response.
According to the analysis, the prevalence of dyslipidemia in granuloma annulare patients was 79.
HIV-associated granuloma annulare (HAGA): a report of six cases.
Granuloma annulare and human immunodeficiency virus infection.
Chronic hepatitis C virus infection associated with a generalized granuloma annulare.
The bland cytology and pseudogranulomatous appearance of classic-type ES in the dermis can lead to misinterpretation as granuloma annulare, chronic granulomatous inflammation (especially rheumatoid nodules), or other necrotizing granuloma (especially necrobiosis lipoidica).
Epithelioid sarcoma masquerading as perforating granuloma annulare.