growth cone

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growth cone

[′grōth ‚kōn]
(neuroscience)
A specialized structure at the end of a growing nerve fiber that guides the fiber to its destination during the development of the nervous system by means of interaction with signaling molecules in its surroundings and its own motile mechanism.
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References in periodicals archive ?
As a circuit is being built, RNAs in the neuron's growth cones are mostly silent.
Focusing on the affects of action potential induced depolarization, Hung and Colicos sought to extend previous findings and investigate how axonal growth cones respond to actual physiological stimulation in spatially displaced neurons.
The growth cones of the pioneering axons are larger and more complex than the subsequent growth cones, signifying the complex environmental cues they must sort through (Bak & Fraser, 2003).
Introduction to cytoskeletal dynamics and pathfinding of neuronal growth cones.
Identification of an invariant response: Stable contact with Schwann cells induces veil extension in sensory growth cones.
Growth cones are not required for initial establishment of polarity or differential axon branch growth in cultured hippocampal neurons.
It also marks the first time aggregate growth cones were used in FOMC policy deliberations.
Bryan argued that his reserve growth cones, reproduced as Chart 3, allowed the FOMC to track the behavior of reserves relative to the path stated in the directive.
Bryan's introduction of reserve growth cones served to reinforce the attack on the language and intent of the directive.
Bryan used his reserve growth cones to propose a February target range of $18,535 million to $18,635 million for total effective reserves.
It's a very clear proof that these proteins are playing an instructive role in giving a direction to the growth cones," Culotti says.
Because this enhancement occurs even when growth cones have been separated from the cell body (the site of protein synthesis), no new protein is required.