Guanidine

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Related to Guanidines: guanidinium

guanidine

[′gwän·ə‚dēn]
(biochemistry)
CH5N2 Aminomethanamidine, a product of protein metabolism found in urine.

Guanidine

 

(also carbamidine). (H2N)2C=NH, colorless hygroscopic crystals; melting point, approximately 50° C. Guanidine absorbs C02 and moisture from the air and forms salts with acids. On hydrolysis it gives urea and ammonia.

Guanidine (or its salts) is obtained by reacting cyanamide with ammonia (or with ammonium salts).

H2N—C≡N + NH3→(H2N)2C═NH

H2N —C≡N +NH4Cl→(H2N)2C═NH.HCI

Guanidine is used to obtain medicinal and explosive substances and ion-exchange resins. A guanidine fragment enters into the composition of guanine (a component of nucleic acids), creatine, and arginine, the antibiotic streptomycin, and tetrodotoxin, a poison of animal origin.

References in periodicals archive ?
The bases included are well-known anilines, pyridines, simple amines, phosphines, guanidines, amidines, and porphyrins.
Phosphagens are phosphorylated guanidine compounds that are involved in buffering cellular ATP levels.
Compounds' ingredients: bis(3-triethoxysilylpropyl) tetrasulfide (TESPT) (Si 69, Evonik); ZnO (Zincol Ossidi); stearic acid (Sogis); sulfur (Solfotecnica); N-tert-butyl-benzothiazol-2-sufenamide (TBBS) (Flexsys); N-N/-di-phenyl guanidine (DPG) (Rhenogran DPG80) (Rhein Chemie Additives).
Coverage encompasses all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines, and metal-NO complexes.
Only a few accelerator families are available to achieve this task, including dithiophosphates, caprolactams, guanidines and thioureas.
Rubber chemicals featured include accelerators and activators (aldehydeamines, dithiocarbamates, guanidines, sulfenamides, thiazoles, thioureas, thiurams and others), antioxidants, antiozonants and protective agents, peptizers, retarders, coagents, peroxides and carbon blacks.
Most sulfenamides, thiazoles, guanidines, thiurams and some dithiocarbamate accelerators are IMDG Class 9 environmentally hazardous materials and toxic to aquatic organisms.
Accelerators described include sulfenamides, guanidines, thiurams, dithiocarbamates, thioureas and specialty curatives.
Compound 10, containing a high sulfur cure and a guanidine accelerator, shows the guanidines to be easily bondable, although it suggests that C8007/8210 is not the best choice.