Guanosine


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to Guanosine: guanosine monophosphate

guanosine

[′gwän·ə‚sēn]
(biochemistry)
C10H13O5N5 Guanine riboside, a nucleoside composed of guanine and ribose. Also known as vernine.

Guanosine

 

the nucleoside consisting of the carbohydrate ribose and the nitrogen base guanine. Colorless crystals. Molecular weight, 283.26 and melting point. 235° C. Free guanosine is an intermediate product of metabolism. It is a component of nucleic acids and biologically active guanyl nucleotides, GMP, GDP. and GTP. GTP (guanosine triphosphate), an energy-rich phosphorus compound, is a coenzyme of some reactions, such as the amination of inosinic acid and the transference of amino acids to ribosomes during the biosynthesis of protein.

References in periodicals archive ?
5'-carboxy guanosine, bio-conjugation, nucleic acid synthesis
KP-1212 can replace cytidine when the viral enzyme reverse transcriptase is building a new copy of HIV, and pair normally with guanosine.
For 2-deoxyinosine, adenosine, 2-deoxyadenosine, guanosine, 2-deoxyguanosine, succinyladenosine, orotic acid, thymine, dihydrouracil, dihydrothymine, uridine, 2-deoxyuridine, and 5-hydroxymethyluracil, sample concentrations were below the lower limits of quantification, as were the concentrations of inosine and N-carbamyl-[beta]-aminoisobutyric acid for children older than 1 year and N-carbamyl-[beta]-alanine for children older than 4 years of age.
Sildenafil dilates penile arteries through cyclic guanosine monophosphate (cGMP), and penile erection is achieved by increasing penile blood flow.
Guanosine 5'-triphosphate (GTP) plays a pivotal role in many
Mammalian cells, in contrast, convert fucose from their surroundings into a form called guanosine diphosphate-fucose (GDP-fucose), which they attach to their surface proteins.
They found that Viagra, by elevating levels of a compound in cells called cyclic guanosine monophosphate, or cGMP, actually encourages platelets to aggregate, thus amending 20 years of scientific claims that the compound acts to prevent platelet aggregation.
b) GC= (Guanosine (G) + Cytidine (C))/ (Adenosine (A)+ Thymidine (T)+ Guanosine (G) + Cytidine (C)) x 100 Table 2.
The same effect was seen with a sugar-like molecule called cyclodextrin, guanosine monophosphate, DNA, and table salt.
16] This in turn stimulates activation of guanine nucleotide exchange factors, which promote the formation of the active guanosine triphosphate (GTP)-bound form of Ras.
Unblocking may also occur with guanosine analogs, such as abacavir (Ziagen), perhaps explaining the diminished response to abacavir in patients with pre-existing zidovudine resistance.