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The hydroethanolic extract of Guibourtia tessmannii showed a higher polyphenolic content (70.
Table 1: Antioxidant activity of Guibourtia tessmannii.
Effect of Guibourtia tessmannii extracts on blood lipids and oxidative stress markers in triton WR-1339 induced hyperlipidemic rats Administration of tyloxapol (triton WR-1339) caused a significant increase (p<0.
Oral administration of Guibourtia tessmannii extracts at dose of 200 mg/kg with an atherogenic diet for 30 days prevented the elevation of plasma total cholesterol, triglycerides LDL-C, TC/HDL and LDL/HDL ratio.
Treatment with Guibourtia tessmannii extracts lead to a significant reduction in transaminases activity as well as creatinine level.
Guibourtia tessmannii has been considered useful in neurodegenerative diseases such as hypertension, atherosclerosis and malaria.
The administration of Guibourtia tessmannii extracts one day after induction of hyperlipidemia significantly inhibited the rise in cholesterol level in this model.
Treatment with Guibourtia tessmannii extracts caused a significant decrease in mean serum TC and LDL-C while increasing HDL-C.