Guthrie test


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Guthrie test

[′gəth·rē ‚test]
(pathology)
A screening test for the detection of phenylketonuria in which the inhibition of growth of a strain of Bacillus subtilis by a phenylalanine analog is reversed byL-phenylalanine, as found in elevated concentration in the plasma of patients with phenylketonuria.
References in periodicals archive ?
South Yorkshire Police, who launched a cold case review into the disappearance, organised for DNA to be extracted from a heel prick blood test, called a Guthrie test, which was taken by a hospital when Ben was born.
All newborns are given the Guthrie test which picks up conditions affecting about one in 40,000 babies.
The inquiry team homed in on the missing girl's Guthrie Test - a blood sample taken shortly after birth from all babies.
While quite likely, we could have devised a list far greater than 7 Wonders that just encompasses medical breakthroughs for those with disabilities, EP ranks the following two as highly significant because of their historical qualities, their far-reaching impact, and the fact that they represent discoveries that sought to prevent a disabling condition altogether or lessen its impact, the Guthrie test and the polio vaccine.
2-mm (1/8-inch) spots were punched from Guthrie test cards by an automated punching device and transferred to a 96-well microtiter plate.
They often ask doctors whether this Guthrie test is really necessary.
The Guthrie test measures the amount of phenylalanine in the blood.
Guthrie's screen for MSUD is still used by many states, but Texas doesn't use the Guthrie test, either.