human leukocyte antigen

(redirected from HLA antigen)
Also found in: Dictionary, Medical.

human leukocyte antigen

[¦yü·mən ¦lü·kə‚sīt ′ant·i·jən]
(immunology)
Any of a group of antigens present on the surface of nucleated body cells that are coded for by the major histocompatibility complex of humans and thus allow the immune system to distinguish self and nonself. Abbreviated HLA.
References in periodicals archive ?
Fearing GVHD, physicians generally refuse to attempt bone marrow transplants that involve more than a single HLA antigen mismatch.
As the differences in HLA antigens increase, the chances of graft-versus-host disease and the severity of the disease is much greater.
A matching system for living donors is essential since about 36% of living donor-recipient pairs will likely be blood-type incompatible, and about 30% of the patients currently on the waitlist for a kidney have HLA antigen desensitization," Montgomery said.
A match is determined by checking proteins called HLA antigens present on cells from the donor and recipient.
HLA antigens in Behcet's disease: a reappraisal by a comparative study of Turkish and British patients.
Each person has a unique set of HLA antigens, inheriting one set from each parent, resulting in thousands of possible HLA types in the population.
Objective: The aim of our study was to investigate the association of HLA antigens and a non-HLA protein D8/17 with rheumatic heart disease and its pattern of cardiac involvement.
HLA antigens are encoded for by the major histocompatibility complex (MHC) region of genes on the short arm of chromosome 6 (1).
2]-MG levels have been anticipated to represent the turnover of HLA antigens and are associated with lymphocyte proliferation and activation (Bjerrum et al.
With its examination of HLA typing, PCR-SSP typing and HLA antigens, this handbook primarily focuses on these issues within new research in hematopoietic stem cells.