human papillomavirus

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human papillomavirus

(HPV), any of a family of more than 60 viruses that cause various growths, including plantar wartswart,
circumscribed outgrowth of the skin caused by a filterable virus that is readily transmitted. Warts may appear anywhere on the skin but are most common on the hands.
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 and genital warts, a sexually transmitted diseasesexually transmitted disease
(STD) or venereal disease,
term for infections acquired mainly through sexual contact. Five diseases were traditionally known as venereal diseases: gonorrhea, syphilis, and the less common granuloma inguinale, lymphogranuloma venereum, and
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. Detectable warts can be or removed, usually by chemicals, freezing, or laser, but often recur. Intralesional alpha interferon has been effective in the treatment of genital warts. Genital warts, sometimes called condylomata acuminata, are soft and often occur in clusters. They can occur internally or externally, but even in the absence of warts the virus may be present and transmittable. Problems can result from untreated warts, which can grow quite large, or, in rare cases, from infection of an infant during delivery. In addition, certain strains of HPV are associated with cancercancer,
in medicine, common term for neoplasms, or tumors, that are malignant. Like benign tumors, malignant tumors do not respond to body mechanisms that limit cell growth.
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 of the cervix, vulva, vagina, penis, and anus, and HPV 16 has been shown to be associated with some forms of Kaposi's sarcoma (see AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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) and throat cancer. A vaccine approved by the Food and Drug Administration in 2006 can protect a woman against those strains that cause most cases of cervical cancer and genital warts, and a study has shown it may also protect against related throat cancers; HPV vaccination is now recommended for both girls and boys beginning at 11 to 12 years of age.

human papillomavirus

[¦yü·mən ‚pap·ə′lō·mə ‚vī·rəs]
(medicine)
One of a family of more than 100 different viruses, most commonly spread via sexual contact, that cause warts on the hands and feet and in the genital area; several types are associated with premalignant and malignant changes in the cervix. Abbreviated HPV.
References in periodicals archive ?
There was a significant correlation observed between an initial negative high-risk HPV test, the regression of cytologic lesions, and the absence of CIN 2/3 in follow-up," Dr.
25] Others have found HPV test results to be intermediate between those documented in these studies and the results by Ferris.
The digene HPV Test is the world's most proven tool for sensitive, early detection of high-risk HPV, and the latest study confirms the benefits which are demonstrated in more than 300 previous peer-reviewed articles, said Dr.
The cobas HPV Test is the only FDA approved assay that provides pooled data for known high risk genotypes and at the same time provides individual results for the two highest risk genotypes, HPV 16 and HPV 18, Roche said.
As mentioned earlier, for women who have a negative cytology test and a positive HPV test, clinicians can either do a repeat co-test in 12 months or do a genotype test for HPV 16 or 16/18.
We discovered that the low-risk HPV test--which has no clinical indications and is not recommended by any guidelines--was actually part of an older version of the HPV test, which tested for both low- and high-risk HPV types," lead author Dr.
We discovered that the low-risk HPV test - which has no clinical indications and is not recommended by any guidelines was actually part of an older version of the HPV test, which tested for both low-and high-risk HPV types," lead author Dr.
Even though a recent Centers for Disease Control and Prevention (CDC) survey indicates that 66% of clinicians who provide cervical screening already used co-testing by 2004, (1) recent estimates are that only one third or fewer of women 30 years or older are being screened with a Pap test + HPV test.
Food and Drug Administration (FDA) for cervical cancer screening via HPV Testing Alone, yet many of the studies cited by the USPSTF did not use this HPV test.
Pap tests performed every three years are marginally less sensitive for detecting abnormal cells than an HPV test done every five years.
In addition to the powerful clinical benefits of the cobas HPV test, Roche now caters to the needs of both low-to-mid volume labs and high-throughput labs who want to consolidate a multitude of validated assays onto a single platform,' said Roland Diggelmann, CEO Roche Diagnostics.
Two-sided t tests and Kruskal-Wallis tests were used to test associations with the monthly HPV test volume.