Hayflick limit


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Hayflick limit

[′hā‚flik ‚lim·ət]
(physiology)
The finite replicative capacity of normal somatic cells.
References in periodicals archive ?
For example, one is to find a way to overcome the Hayflick limit on cell reproduction.
This phenomenon is known as the Hayflick limit, after Leonard Hayflick, who with Paul Moorhead described it in 1961 while at the Wistar Institute in Philadelphia.
That telomere shortening is directly responsible for the Hayflick Limit is doubtful, but the discovery of telomerase led some entrepreneurs, scientists, and media persons to believe that it was the key to curing cancer and also a Holy Grail for extending human lifespan.