hemoglobin A

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Related to Hb A: HBO, Hb F, Hb A 1c

hemoglobin A

[′hē·mə‚glō·bən ′ā]
(biochemistry)
The type of hemoglobin found in normal adults, which moves as a single component in an electrophoretic field, is rapidly denatured by highly alkaline solutions, and contains two titratable sulfhydryl groups per molecule.
References in periodicals archive ?
Hb Average RBC Lifespan in Days (n) Hb A 120 Hb S 93 (3) (20) Hb E No Data Hb C 87 (6) (18) Hb D 115 (3) (19) Table 2.
1c] can be separated from Hb A because glycation of the N-terminal valine decreases the positive charge.
Several methods, including the D-10, DiaSTAT, Dimension RxL, DS5, HA8160, and VARIANT II, showed increased scatter when samples containing Hb C or S trait were tested compared with that seen for samples homozygous for Hb A.
HPLC and electrophoretic findings include absence or marked reduction in Hb A with a variable Hb F concentration.
Our data for Hb AS samples with the Diamat method were not consistent with previous results (5, 6).
This variant eluted after Hb A in both the Variant (Fig.
Samples from patients homozygous for Hb A served as controls for detecting calibration differences between methods.
2], Hb E, Hb A, and Hb F was performed by the BTS program; quantitation of Hb Bart's was performed by the ATS program on the Bio-Rad VARIANT, a fully automated HPLC system that uses double wavelength detection (415 and 690 nm).
Hb A, assay of the red cell hemolysates of the specimens was carried out with an automated Diamat HPLC system (BioRad), which involved a spherical cation-exchange gel column and a 5-min step-gradient created by a single-piston pump and three phosphate buffers of increasing ionic concentration.
A Hb electrophoresis panel consisting of a screen for sickle Hb, quantification of Hb fractions (normally Hb A, Hb [A.