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heart transplant
(redirected from Heart transplantation)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.

heart transplant

Procedure to remove a diseased heart and replace it with a healthy one from a legally dead donor. The first was performed in 1967 by Christiaan Barnard. The diseased heart is removed (except for some atrial tissue to preserve nerve connections to the natural pacemaker). The new heart is put in place and connected to the recipient's blood vessels. Patients and donors are matched for tissue type, but the patient's immune system must still be suppressed to prevent rejection (see immunosuppression). A successful transplant can enable the recipient to have an active life for many years.



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About five years ago, doctors found out that the new generation of LVADs can be used as "a destination therapy" for patients who are not candidates for heart transplantation.
Women with HF tend to have a better prognosis for any given peak oxygen consumption value when compared to men, yet the cut-off values to determine need for heart transplantation are the same for both sexes.
This first clinical heart transplantation stimulated world-wide interest, and many surgeons quickly co-opted the procedure.
 
 
 
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