Hemagglutinins


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Hemagglutinins

 

antibodies capable of stimulating the agglutination of red blood cells. Hemagglutinins are subdivided into autohemagglutinins, which act on the blood cells of one’s own body, homohemagglutinins, which act on the red blood cells of organisms of the same species, and heterohemagglutinins, which act on the blood cells of other animal species. Some hemagglutinins are active only against red blood cells suspended in an isotonic sodium chloride solution, and others only in the presence of hydrophilic colloids, such as albumin, or after preliminary action on red blood cells by a proteolytic enzyme. Special hemagglutinins, called frigohemagglutinins, manifest activity only at a temperature of about 4° C.

References in periodicals archive ?
Think of hemagglutinin as a miniature broccoli stalk.
Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.
This is why universal flu vaccine strategies in recent years have been focused more on the hemagglutinin stem than on the head," noted Damian C.
One of the mutations Kawaoka found in the hemagglutinin molecule may already be helping the virus adapt to humans.
2009) Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957.
French bean hemagglutinin isolated in the present investigation displays an N-terminal sequence similar to those of hemagglutinins from other Phaseolus vulgaris cultivars and Phaseolus species.
In parallel to IgG detection for control groups, we also evaluated IgG levels against seasonal influenza virus hemagglutinins H1 and H3 by ELISA of the 15 paired serum samples (Figure 3, panel A).
The drop in pH alters the shape of the viral hemagglutinin, thereby allowing the virus to fuse to the cell and open an entry for the virus' RNA to come in and start making fresh viruses.
We tested only for seroreactivity to the H5 hemagglutinin and the N1 neuraminidase; therefore, further studies are needed to determine whether different avian origin influenza viruses are present in the guinea pig population.
double dagger]) Reassortant virus possessing the hemagglutinin and neuraminidase genes of A/Minnesota/11/2010 and the remaining 6 genes of A/PR/8/34.
The hemagglutinin contained 5 conserved amino acid differences that distinguish canine from equine lineages.