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see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
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the nonprotein component (the so-called prosthetic group) and the coloring matter of hemoglobin.

Chemically, heme is a compound of protoporphyrin and divalent iron. In the vertebrate body heme is synthesized from simpler nitrogen compounds (glycine and succinate) and from ferritin, a reserve iron-protein complex present in the spleen, liver, and bone marrow. The heme isolated from the blood of various vertebrates always has the same structure:

Free heme readily oxidizes in air to hematin, in which the iron atom is trivalent. Many years of research on the structure of heme were rewarded by the synthesis in 1929 by H. Fischer of hemin, the hydrochloride of heme.


C34H32O4N4Fe An iron-protoporphyrin complex associated with each polypeptide unit of hemoglobin.
References in periodicals archive ?
Mr Heming said Mr Curran had suffered a significant head injury and surgeons were unable to operate.
Bruce Willis got steamy with his wife Emma Heming on the red carpet in Berlin at the premiere of A Good Day To Die Hard.
But because Heming could not be found, the coroner recorded a verdict of 'murder by persons unknown'.
I can't think of another group of people who work at really hard jobs, FAMILY GUY: Willis with, from left, Ashton Kutcher, Demi Moore, Micah Alberti, Rumer Willis, Emma Heming, Tallulah Belle Willis, unidentified guest, and Scout Willis who get shot at every night for their jobs, and who could use an opportunity to go out and have a good laugh.
I hope that all will benefit from the event," said Prof Al Bastaki, Prof Al Bastaki will be among seven chief speakers, including World Renewable Energy Network director-general and WREC chairman Prof Ali Al Sayegh, National Renewable Energy Laboratory director of science and technology cooperation Dr Lawrence L Kazmerski, Wind Direct Limited managing director Martin Alder, Riomay Solar Heating Company managing director Tony Book, Schott Solar AG Company chief executive officer Dr Martin Heming and UoB faculty members Dr Hussain Al Madani and Dr Shaker Haji.
LOS ANGELES: Film star Bruce Willis, 54, of "Die Hard" fame, has tied the knot with model Emma Heming, in a Caribbean island ceremony attended by his ex-wife Demi Moore and their three daughters, his spokesman said Sunday.
HOLLYWOOD superstar Bruce Willis has married model Emma Heming for the second time in a week.
He is survived by his wife of 62 years, Eva Mae Piper; his son, Jon of Leicester, MA; his daughter, Carol Heming of Warrensburg, MO; also three grandchildren, Michael, Valerie, Jaymie; and three great-grandsons, Jurgen, Richard, and Mathew.
announces several appointments: Michael McNichols named national sales manager; Scott Heming appointed special projects manager; and Chuck Cobb, southeast regional manager .
Everybody is filing their taxes at the last minute,'' said Beth Ann Heming, office manager at the H&R Block office in Canyon Country.
Heminge, Johnalso spelled Heming, Hemminge, or Hemmings(b.
COM Editor-in-Chief, Zhao Heming added, "We are very excited to be bringing a new source of market information to China.