Hemoglobinuria


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Related to Hemoglobinuria: Hemosiderinuria, paroxysmal nocturnal hemoglobinuria

hemoglobinuria

[‚hē·mə‚glō·bə′nu̇r·ē·ə]
(medicine)
A pathological condition in which the urine contains hemoglobin.

Hemoglobinuria

 

the presence of hemoglobin in urine. It usually is a result of the intravascular decomposition of red blood cells following the transfusion of incompatible blood, the effect of some chemical and biological poisons and drugs that cannot be tolerated or of any of several causative agents of infections, extensive injuries, and so on.

References in periodicals archive ?
Analysis of key recent licensing and partnership agreements in Paroxysmal Nocturnal Hemoglobinuria Therapeutics market
Pediatric patients had substantial morbidity related to chronic uncontrolled complement activation and hemolysis with impaired renal function (13%), thrombosis (11%), fatigue (63%), abdominal pain (45%), dyspnea (41%), dysphagia (20%), and hemoglobinuria (66%).
4) Abstract 833 entitled "Pediatric diagnosis of paroxysmal nocturnal hemoglobinuria in the International PNH Registry," presented by Dr.
Eculizumab Treatment of Paroxysmal Nocturnal Hemoglobinuria Relapsing After Bone Marrow Transplant and Subsequent Clonal: Case Report," Brodsky, et al.
We look forward to advancing Coversin into Phase 2 development in patients with Paroxysmal Nocturnal Hemoglobinuria, and to address a significant unmet need in the treatment of patients resistant to eculizumab.
25] Three cases of paroxysmal nocturnal hemoglobinuria with renal hemosiderosis and renal failure were reported by Nair and colleagues.
This report provides insights into the up-and-coming trends of the acquired orphan blood disorder pharmaceutical market by examining Idiopathic Thrombocytopenic Purpura (ITP), Myelodysplastic Syndrome (MDS), Myelofibrosis (MF), Paroxysmal Nocturnal Hemoglobinuria (PNH) and Polycythemia Vera (PV) in seven major markets: the US, the top five European countries (France, Germany, Italy, Spain and the UK) and Japan.
Soliris is approved in the US, European Union, Japan and other countries as the first and only treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), a debilitating, life-threatening and ultra-rare blood disorder.
Dark brown urine can be caused by foods, medications, bilirubin, hematuria or hemoglobinuria, and myoglobinuria.
A recent development in flow cytometry has been increased testing for paroxysmal nocturnal hemoglobinuria (PNH).