Henderson, Richard,1735–85, American colonizer in Kentucky, b. Hanover co., Va. An associate justice of the North Carolina superior court (1769–73), Henderson was long interested in Western lands and was the chief promoter of the Transylvania CompanyTransylvania Company,
association formed to exploit and colonize the area now comprising much of Kentucky and Tennessee. Organized first (Aug., 1774) as the Louisa Company, it was reorganized (Jan., 1775) as the Transylvania Company.
..... Click the link for more information. . He followed (1775) Daniel BooneBoone, Daniel,
1734–1820, American frontiersman, b. Oley (now Exeter) township, near Reading, Pa.
The Boones, English Quakers, left Pennsylvania in 1750 and settled (1751 or 1752) in the Yadkin valley of North Carolina.
..... Click the link for more information. , an agent for the company, to the company's first settlement at Boonesboro on the Kentucky River and in 1779 employed James RobertsonRobertson, James,
1742–1814, American frontiersman, a founder of Tennessee, b. Brunswick co., Va. He was reared in North Carolina. After the failure of the Regulator movement, he led (1771) a group of settlers from Orange co., N.C.
..... Click the link for more information. to settle the Cumberland River area. Virginia and North Carolina voided the company's land grants, and Henderson and his associates were left with a very small portion of the vast territory they had claimed. Although primarily a land speculator, Henderson was one of the most important figures in the early expansion of the frontier.
See A. Henderson, The Conquest of the Old Southwest (1920); W. S. Lester, The Transylvania Colony (1935).
Henderson, Richard,1945–, Scottish molecular biologist, Ph.D. Cambridge, 1969. Henderson has been a researcher at the Laboratory of Molecular Biology in Cambridge since 1973. In 2017 he was awarded, with Joachim FrankFrank, Joachim,
1940–, German-American physicist and biochemist, b. Siegen, Germany, Ph.D., Technical Univ. of Munich 1970. He became a U.S. citizen in 1997. Following several postdoctoral appointments, Frank joined the New York State Department of Health as a researcher
..... Click the link for more information. and Jacques DubochetDubochet, Jacques,
1942–, Swiss biophysicist and molecular biologist, Ph.D., Univ. of Geneva 1973. Dubochet was a researcher at the European Molecular Biology Laboratory in Heidelberg from 1978 to 1987, when he joined the faculty at the Univ.
..... Click the link for more information. , the Nobel Prize in Chemistry for work in developing cryo-electron microscopy, which permits the high-resolution determination of the structure of biomolecules in solution. It had long been believed that electron microscopes were unsuitable for imaging biological material because the electron beam is destructive. In 1990, however, Henderson successfully used the technology to produce a three-dimensional image of a protein at atomic resolution. Cryo-electron microscopy enables researchers to visualize previously unseen processes, advancing both the basic understanding of life's chemistry and the development of pharmaceuticals.