The USPIs for VIEKIRA PAK and TECHNIVIE were updated following post-marketing reports of hepatic decompensation and hepatic failure
, including liver transplantation or fatal outcomes, in patients receiving AbbVie's HCV treatment, with or without RBV.
Very rarely these reports have involved hepatic failure
, with and without a fatal outcome, although causality has not been established.
Patients who are pregnant or have renal or hepatic failure
, uncontrolled hypertension, sepsis, or vascular disease, should not take DHE, Dr.
Average survival is 6 months, with death resulting from hepatic failure
in 50% of patients and from intra-abdominal hemorrhage in 25%.
However, his condition rapidly deteriorated to hepatic failure
The next stage is vomiting, diarrhea, renal and hepatic failure
and in some cases patients have a mass haemorrhage and at the final stage multi organ failure.
Fulminant hepatic failure
(FHF) is a life-threatening clinical syndrome and characterized by coagulopathy, jaundice and multisystem organ failure and a very high mortality, even though there is still no available therapy except liver transplantation limited by the chronic shortage of donor livers (Van Thiel et al.
WASHINGTON--Signals for several hematologic toxicities and for hepatic failure
were identified in an analysis of serious adverse drug reactions associated with boceprevir treatment, according to an analysis of Food and Drug Administration data.
Vishwajeet, 22, is suffering from a severe liver ailment -- fulminant hepatic failure
Hepatic dysfunction is a common feature of multiple organ dysfunction syndrome, and hepatic failure
is the most lethal factor in multiple organ dysfunction syndrome.
In fulminant hepatic failure
and chronic liver diseases, the AT3 level decreases.
Niacin use has been somewhat limited by the adverse reaction of flushing and reports of infrequent but serious hepatotoxicity, including fulminant hepatic failure