hepatotoxin

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Related to Hepatotoxins: nephrotoxins

hepatotoxin

[¦hep·əd·ō′täk·sən]
(pharmacology)
An agent capable of damaging the liver.
References in periodicals archive ?
Information obtained from the patients' medical records included date of birth, gender, site of TB, basis of diagnosis, phase of treatment, symptoms, comorbid conditions, hepatotoxin ingestion (including prescription medication, traditional or herbal remedies, and alcohol), HIV status, CD4 count, ART details, serial liver function tests (LFTs), viral hepatitis studies, abdominal ultrasound findings and TB drug reintroduction details.
In the present study compounds isolated from the ethyl acetate fraction of methanol extract were examined against the hepatotoxin in vitro using primary cultured rat hepatocytes.
Cyanobacterial hepatotoxins can kill an animal within 24 hours, says Michele A.
Although the possibility of an acute lethal dose reaching the consumer through the drinking-water supply can be excluded--an adult would have to ingest a huge quantity of a toxic bloom to receive such a dose--the existence of gastrointestinal disorders linked to the ingestion of cyanobacterial toxins, as well as the chronic risks posed by hepatotoxins, make the toxins of blue-green algae a serious threat to human health when they are present in drinking-water supplies.
5 Hepatocytes as a Model for Screening Food-Related Hepatotoxins and Studying Mechanisms of their Toxicity (Saura C.
The whole extract and the active lignans in the extract have been well proven to possess hepatoprotective effect against the hepatic dysfunction induced by various chemical hepatotoxins such as carbon tetrachloride (C[Cl.
Apart from a detailed drug history, including the possible intake of herbal medicines or exposure to hepatotoxins, an initial laboratory evaluation of patients with acute liver failure should include testing for hepatitis A, B, and C.
18) Sweet potatoes or legumes may produce hepatotoxins as well as compounds able to produce neuropathy and mental confusion.
Cyanobacteria produce a complex mixture of hepatotoxins and neurotoxins.
19) It is recommended that patients avoid abdominal trauma in the presence of splenomegaly and refrain from hepatotoxins until liver abnormalities resolve.