When the expression of LXR[alpha] gene is increased, more heterodimers
could be formed by PPARI3 and RXR, inhibiting PPARI3 and RXR forming heterodimers
and decreasing the expression of PPARI3 (Yoshikawa et al.
is involved in constitutive expression of the housekeeping Na,K-ATPase alpha 1 subunit gene.
PPAR/retinoid X receptor (RXR) heterodimers
bind to these response elements through the PPAR DNA binding domain, which is a highly conserved domain similar to various transcription factors (1), (2).
This relates to the possible formation of heterodimers
of exogenous MTP1 with endogenous MTP1.
This receptor is mainly expressed in the adipose tissue and it forms heterodimers
with Retinoid X Receptors, which bind to specific regions of the DNA of target genes and regulate their expression.
Research and development company for cancer drugs Eutropics Pharmaceuticals announced on Tuesday that the US Patent and Trademark Office has issued patent number 8,168,755 entitled, "Antibodies specific to heterodimers
of Bcl-2 family and uses thereof".
In an effort to locate the C9 binding site on C8[alpha], truncated and chimeric C8[alpha] in which modules were deleted or exchanged for those in C8[beta] were expressed independently or as heterodimers
with C8[gamma] and combined with C8[beta].
In particular, the discovery that microbial triacylated lipoproteins activate TLR2/1 heterodimers
, whereas diacylated lipoproteins activate TLR2/6 heterodimers
arose from work with the M.
In a large variety of tissues, RARs act by forming heterodimers
with one of the rexinoid receptors, retinoid X receptor (RXR; [alpha], [beta], or[gamma] isotypes), which bind 9-cis but not atRA (Mark et al.
Some studies have shown the role of Nrf2-MafK heterodimers
in the activation of ARE-mediated gene expression (41).
Quantification of soluble HLA class I heterodimers
and beta 2-microglobulin in patients with active pulmonary tuberculosis.
Extend the Lipton Study in metastatic breast cancer by making additional VeraTag measurements, such as those for p95, HER3 and HER heterodimers
, in existing patient samples to investigate the relationship between those biomarkers and clinical outcomes, and subsequently submitting study results for presentation and publication.