infectious mononucleosis (redirected from Heterophile test)

infectious mononucleosis

an acute infectious disease, caused by Epstein-Barr virus, characterized by fever, sore throat, swollen and painful lymph nodes, and abnormal lymphocytes in the blood

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infectious mononucleosis [in′fek·shəs ‚män·ō‚nü·klē′ō·səs]

(medicine)

A disorder of unknown etiology characterized by irregular fever, pathology of lymph nodes, lymphocytosis, and high serum levels of heterophil antibodies against sheep erythrocytes. Also known as acute benign lymphoblastosis; glandular fever; kissing disease; lymphocytic angina; monocytic angina; Pfeiffer's disease.

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Infectious mononucleosis

A disease of children and young adults, characterized by fever and enlarged lymph nodes and spleen. EB (Epstein-Barr) herpesvirus is the causative agent.

Onset of the disease is slow and nonspecific with variable fever and malaise; later, cervical lymph nodes enlarge, and in about 50% of cases the spleen also becomes enlarged. The disease lasts 4–20 days or longer. Epidemics are common in institutions where young people live. EB virus infections occurring in early childhood are usually asymptomatic. In later childhood and adolescence, the disease more often accompanies infection—although even at these ages inapparent infections are common. See Epstein-Barr virus