Hippuric Acid

(redirected from Hippurates)
Also found in: Dictionary, Medical.

hippuric acid

[hi′pyu̇r·ik ′as·əd]
(organic chemistry)
C6H5CONHCH2·COOH Colorless crystals melting at 188°C; soluble in hot water, alcohol, and ether; used in medicine and as a chemical intermediate.

Hippuric Acid

 

benzoylglycine, C6H5CONHCH2COOH, a compound consisting of benzoic acid and glycine groups; colorless, crystalline; melting point, 187.5° C.

Hippuric acid is formed in most animals and in man, primarily in the liver, and passes out in the urine. The biological significance of hippuric acid synthesis in the body is in the binding of benzoic acid, which is liberated during the destruction of the aromatic compounds that are a part of the makeup of plant tissues. In clinical practice the liver’s detoxication ability is measured by a test for hippuric acid synthesis (Quick’s test).