Hirsutism


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hirsutism

[′hər·sə‚tiz·əm]
(medicine)
An abnormal condition characterized by growth of hair in unusual places and in unusual amounts.

Hirsutism

 

masculine type of hairiness in women; one of the manifestations of virilism. The term “hirsutism” was introduced into medical practice in 1910 by the French physician E. Apert.

Hirsutism is most often a symptom of several diseases produced by affection of the adrenal cortex and the sex glands. A symptom resembling hirsutism is also observed with the development of a tumor in the anterior pituitary gland, which is accompanied by increased secretion of the hormone that activates function of the adrenal cortex. Hirsutism is revealed by the appearance of hair on the face (mustache and beard), abdomen, chest, arms, and legs. It may be characterized by the predominance of adiposity (“adipose” hirsutism) with excessive development of blackheads or by sharply expressed masculine traits. In the latter case, the musculature and skeleton of young women resemble those of a man (“muscular” hirsutism), and meat-red spots appear on the body (mainly on the face and legs). Hirsutism in little girls is often accompanied by premature development of the external sex organs and of secondary sexual characteristics of the male, underdeveloped internal sex organs, absence of menstruation, enlargement of the mammary glands (owing to fatty, not glandular, tissue), and roughening of the voice; there is psychological and intellectual retardation, and sexual feeling is absent. Treatment of hirsutism calls for surgery and X-ray therapy.

Hairiness is sometimes observed also in women during the climacteric, when there is a decrease in ovarian function. In the absence of the other clinical symptoms observed in pathologic hirsutism, family (genetic) hirsutism, which develops in young women, often in the period of sexual maturation, presents a special picture. This type is apparently the result of an increased sensitivity of the hair bulbs to the normal male-hormone content in the woman’s body. The treatment for this form of hirsutism consists in local attack on the hair bulbs—electrocoagulation and electrolysis.

L. M. GOL’BER

References in periodicals archive ?
Seventy-two to 82% of women with hirsutism who present with a history of and/or physical exam findings of irregular menses, normal to slightly elevated androgen levels, ultrasound results positive for polycystic ovaries, central obesity, lack of fertility, insulin resistance, and acanthosis nigricans are given a diagnosis of polycystic ovary syndrome (Bode et al.
11) Clinical trials of spironolactone for hirsutism have been rated as "low quality" and additional controlled trials of OEP monotherapy versus OEP plus spironolactone are warranted.
So androgens in the circulation remain as free androgens resulting in hirsutism.
15] Depression in PCOS may be related to change in physical appearance as obesity, acne, and hirsutism lead to negative perception of self and social withdrawal, which culminates into depression.
Differences in the assessment of quality of life between patients with symptoms of hirsutism and those not showing any such symptoms are presented in Table 3.
Conclusion Obesity is commonly associated with a wide range of dermatological manifestations like acanthosis nigricans, striae, hirsutism, skin infections.
Statin medications don't alter weight, hirsutism, or menstruation (SOR: B, small meta-analysis).
These results point toward hyperandrogenism, a common cause of hirsutism, acne, and virilization, as a potential mitigating factor for PFB in women," the researchers wrote, adding that the higher prevalence of hormonal disorders in the women's cohort "demonstrates the importance of considering hormonal influences when working-up a female patient with PFB.
High prevalence of the polycystic ovary syndrome and hirsutism in women with type 1 diabetes mellitus.
The clinical examination focused on the evaluation of anthropometric and parametric values (height, weight and waist circumference) and also hirsutism using the Ferriman-Gallwey score (21).
Hirsutism improved significantly in both groups, and the difference between the metformin group and NAC group was not significant.