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Hodgkin's disease |
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Hodgkin's disease, a type of cancer of the lymphatic system lymphatic system (lĭmfăt`ĭk) ..... Click the link for more information. . First identified in 1832 in England by Thomas Hodgkin, it is a type of malignant lymphoma. Incidence peaks in young adults and the elderly. There is some evidence that it is caused by an infection (the Epstein-Barr virus Epstein-Barr virus (EBV), herpesvirus that is the major cause of infectious mononucleosis and is associated with a number of cancers, particularly lymphomas in immunosuppressed persons, including persons with AIDS. ..... Click the link for more information. is sometimes present), and studies of twins suggest a hereditary susceptibility. In addition, exposure to the defoliant, Agent Orange Agent Orange, herbicide used by U.S. forces during the Vietnam War to expose enemy guerrilla forces in forested areas. Agent Orange contains varying amounts of dioxin. ..... Click the link for more information. , has been strongly linked to Hodgkin's disease and other lymphomas. The first sign is often enlarged lymph nodes in the neck or armpit. Lymph node biopsy shows the multinucleated Reed-Sternberg cells peculiar to the disease. It spreads from node to node in an orderly fashion. Symptoms include itching, fever, night sweats, and weight loss. Because it affects the lymphatic system, the body becomes less able to fight off infection as the disease progresses. Radiation therapy and combinations of chemotherapeutic agents are used in treatment. By the 1990s most newly diagnosed cases were curable. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| One patient had high-grade non-Hodgkin's lymphoma in the larger tonsil, and the other had lymphocyte-rich Hodgkin's lymphoma. 5) Hodgkin's lymphoma was not included as an AIDS-defining illness by the Center for Disease Control and Prevention HIV classification system, (5) but data from several studies suggest that the risk of Hodgkin's lymphoma in persons with HIV infection is increased. Phase 2 trials have been initiated in Hodgkin's Lymphoma and in myelofibrosis with myeloid metaplasia. |
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